Long-Term Melatonin Use: Risks To Blood Pressure, Cholesterol And More

While melatonin is widely used to regulate sleep-wake cycles, experts caution that long-term or high-dose use may impact cardiovascular and metabolic health. Evidence suggests it can interfere with blood-pressure medications, hormone levels and lipid profiles. Users should monitor for elevated blood pressure, cholesterol changes and other side-effects, and consult doctors before chronic use—especially in individuals with underlying health risks.

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Long-Term Melatonin Use: Risks To Blood Pressure, Cholesterol And More
Health • 48 days ago • 3392 views

Long-Term Melatonin Use: Risks To Blood Pressure, Cholesterol And More

IN SHORTWhile melatonin is widely used to regulate sleep-wake cycles, experts caution that long-term or high-dose use may impact cardiovascular and metabolic health. Evidence suggests it can interfere with blood-pressure medications, hormone levels and lipid profiles. Users should monitor for elevated blood pressure, cholesterol changes and other side-effects, and consult doctors before chronic use—especially in individuals with underlying health risks.

TL;DR

  • Physicians note melatonin can interact with blood-pressure, sugar-lowering and anticoagulant medications, altering effectiveness.
  • Some users report elevated blood pressure or higher cholesterol levels after extended supplement use, though data remains preliminary.
  • Common side-effects include headaches, dizziness, daytime drowsiness and vivid dreams, particularly at high doses.
  • Supplements are less strictly regulated than medications; users should choose third-party-tested products.
  • Doctors emphasise that “natural” does not equal “risk-free” and long-term supplementation should be evaluated carefully.
  • For people with cardiovascular or endocrine disorders, regular monitoring is recommended if using melatonin.

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